Do Similar Structures Have Similar No Observed Adverse Effect Level (NOAEL) Values? Exploring Chemoinformatics Approaches for Estimating NOAEL Bounds and Uncertainties

Yang C, Rathman JF, Magdziarz T, Mostrag A, Kulkarni S, Barton-Maclaren TS. “Do Similar Structures Have Similar No Observed Adverse Effect Level (NOAEL) Values? Exploring Chemoinformatics Approaches for Estimating NOAEL Bounds and Uncertainties.” Chemical Research in Toxicology. 2021;34(2):616-633.

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Visit us at SOT 2021

MN-AM.com is attending the upcoming Annual Meeting and ToxExpo Virtual Event of the Society of Toxicology in March 2021.

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Evaluation of the applicability of existing (Q)SAR models for predicting the genotoxicity of pesticides and similarity analysis related with genotoxicity of pesticides for facilitating of grouping and read across: An EFSA funded project.

Benigni R, Serafimova R, Parra Morte JM, et al. “Evaluation of the applicability of existing (Q)SAR models for predicting the genotoxicity of pesticides and similarity analysis related with genotoxicity of pesticides for facilitating of grouping and read across: An EFSA funded project.” Regulatory Toxicology and Pharmacology. 2020;114:104658.

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Release of Version 3.2020 of ChemTunes.ToxGPS

The ChemTunes.ToxGPS software platform for safety and risk assessment of chemical compounds provides a unique combination of an expert-reviewed toxicity database, MoA-based in silico predictions for human health endpoints and workflows to support, e.g., read-across and ICH M7 GTI studies. The final outcomes are weight of evidence-based and obtained from a rigorous decision theory approach.

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Visit MN-AM at SITOX 2020

MN-AM.com is attending the upcoming 19th National Congress of the Italian Society of Toxicology, SITOX 2020, in Bologna, Italy, from February 11-12, 2020.

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