58^th Annual Meeting and ToxExpo of the Society of Toxicology in Baltimore in Maryland, USA, March 10 to 14, 2019

Thank you for visiting us at the SOT 2019. The following presentations and events have been contributed and are available for download below.

Poster Presentations

• Comparative Case Studies to Establish a Standardized Process for Read-Across within a Daily Safety Assessment Workflow
  T. Kawamoto¹, A. Granitzny², J. Rathman^3,4, A. Mostrag³, C. Yang^{3
  1}Kao Corporation, Tokyo, Japan; ²Kao Germany GmbH, Darmstadt, Germany; ³MN-AM, Columbus, OH, USA; ⁴The Ohio State University, Columbus, OH, USA
  Poster Board P134, Abstract 1758
  Tuesday, March 11, 2019
  Poster Session: Computational Toxicology I 
• Development of DILI Prediction Tools for Humans and Mammals from the Vantage of Translational Safety Assessment
  W. Muster¹, D. Naga¹, J. Rathman^2,3, A. Mostrag², C. Yang^{2,3
  1}Hoffmann-La Roche Ltd., Pharmaceutical Scienes, Basel, Switzerland; ²MN-AM, Molecular Networks GmbH, Nuremberg, Germany and Altamira LLC, Columbus, OH, USA; ³Chemical and Biomolecular Engineering Department, The Ohio State University, Columbus, OH, USA
  Poster Board P170, Abstract 1794
  Tuesday, March 12, 2019
  Poster Session: Computational Toxicology II 
• Improving In Silico Assessment of Cosmetic Ingredients by Leveraging In Vivo Data from Public Systems
  Aleksandra Mostrag¹, Jonghyn Kim², JungSoo Kim³, SiJun Park³, Woo-Hyuck Choi⁴, Yooree Lim², Sungmin Yang², Jongjin Park¹, Jörg Marusczyk¹, Christof H. Schwab¹, James F. Rathman^1,5, Chihae Yang^1,5, Mark Cronin⁶, Andrew Worth⁷, Andrea Richarz^{7
  1}MN-AM, Nuremberg, Germany & Columbus, OH, USA; ²Korean Cosmetics Institute of Industries, Osan Korea; ³Advanced Cosmeceutical Technology, Su Won, Korea; ⁴LG Household & Health Care, Seoul, Korea; ⁵The Ohio State University, Columbus, OH, USA; ⁶Liverpool John Moores University, Liverpool, UK; ⁷EC Joint Research Centre, Ispra, Italy
  Poster Board P224, Abstract 1841
  Tuesday, March 12, 2019
  Poster Session: Risk Assessment I 
• New TTC Database Compilation To Support Thresholds Of Toxicological Concern In The Risk Assessment of Antimicrobials Beyond Cramer Classes
  C. Yang^1,2, A. Mostrag¹, J. Rathman^1,2, V. Vitcheva¹, N. Skoulis³, M.A. Cheeseman^{3
  1}MN-AM, Molecular Networks GmbH, Nuremberg, Germany and Altamira LLC, Columbus, OH, USA; ²Chemical and Biomolecular Engineering Department, The Ohio State University, Columbus, OH, USA; ³Steptoe and Johnson LLP, Washington, DC, USA
  Poster Board P326, Abstract 3530
  Thursday Morning, March 14, 2019
  Poster Session Late-Breaking 11: Safety Assessment: Pharmaceutical and Non-Pharmaceutical; Natural Products; Epigenetics 

Oral Presentations

• Prediction of Specific Target Organ Toxicity after Repeated Exposure (STOT-RE) Using NAMs
  Mark CroninTuesday, March 12, 2019 

Special Events

• Molecular Networks and Altamira – COSMOS NG / ToxGPS Reception: Toxicity Data and Workflows to Improve Safety and Risk Assessment
  Sheraton Inner Harbor Hotel, 300 South Charles Street, Baltimore, MD 21201, Potomac Room (3^rd level)
  Monday, March 11, 2019 
• MN-AM: Addressing Safety and Risk Assessment with ChemTunes·ToxGPS
  MN-AM (Molecular Networks & Altamira) presents the unique ChemTunes·ToxGPS platform, a highly curated toxicity and safety evaluation database, a MoA-based prediction knowledgebase, and read-across workflow for the safety and risk assessment of chemicals.
  Convention Center, Room 338
  Tuesday, March 12, 2019