53rd Annual Meeting and ToxExpo of the Society of Toxicology in Phoenix, Arizona, USA, March 23 to 27, 2014
Thank you for visiting us at the SOT 2014. The following presentations and events have been contributed and are available for download below.
Poster Presentations
- Collaborative Interoperability between Public Projects to Support Replacement of In Vivo Repeated Dose Toxicity Testing.
Presented by D. Hristozov
Abstract no. 431 - Threshold of Toxicological Concern (TTC); A Strategy to Support Application of TTC to Dermally Applied Cosmetic Ingredients.
Presented by F.M. Williams
Abstract no. 632 - Development of Noncancer Threshold of Toxicological Concern (TTC) Database to Support Alternative Assessment Methods for Cosmetics-Related Chemicals.
Presented by K. Muldoon-Jacobs
Abstract no. 1609 - Data Mining Approach to Formulate Alerting Chemotypes for Liver Steatosis/Steatohepatitis/Fibrosis.
Presented by A.S. Mostrag-Szlichtyng
Abstract no. 2254 - In silico Workflow for Assessing Skin Irritation, Penetration, and Sensitization Potentials Using Chemotype-Based Models and Alerts.
Presented by J. Rathman
Abstract no. 2273 - Metabolism Simulation and Toxicity Prediction in the Evaluation of Food Ingredient/Contaminant Safety.
Presented by L. Terfloth
Abstract no. 2273d
Special Events
The COSMOS Symposium Session on “Computational Approaches to Predict Repeat-Dose Toxicity: Lessons Learned from Cosmetic Ingredients” was held on Monday morning, March 24, 2014 and chaired by Chihae Yang, Altamira LLC, Columbus, OH, USA, and Mark T. Cronin, Liverpool John Moores University, United Kingdom. The following oral presentations were given.
- Computational Approaches to Predict Repeat-Dose Toxicity: Lessons Learned from Cosmetic Ingredients.
Presented by M.T. Cronin
Abstract no. 26 - Databases, Tools, and TTC Approach Applied to Chemicals in Cosmetics Products.
Presented by C. Yang
Abstract no. 27 - Role of Bioavailability in Risk Assessment of Cosmetic Ingredients: Kinetics, Permeation, and Metabolism.
Presented by E. Fioravanzo
Abstract no. 28 - Adverse Outcome Pathways (AOPs) for Target Organ Effects: The Role of Structural Alerts and Chemotypes for Liver Toxicity to Group Compounds and Apply Read-Across.
Presented by M.T. Cronin
Abstract no. 29 - Applying Databases and Tools from COSMOS to the Scientific Needs of US FDA’s CERES Project.
Presented by K. Arvidson
Abstract no. 30 - US EPA’s ToxCast, Tox21, and COSMOS Projects: Cheminformatics Approaches to Creating Data Linkages and Synergies.
Presented by A.M. Richard
Abstract no. 31