Self-Organizing Maps for Identification of New Inhibitors of P-Glycoprotein.

Self-Organizing Maps for Identification of New Inhibitors of P-Glycoprotein.

Kaiser D, Terfloth L, Kopp S, et al. “Self-Organizing Maps for Identification of New Inhibitors of P-Glycoprotein.” J. Med. Chem.. 2007;50(7):1698-1702. 

TitleSelf-Organizing Maps for Identification of New Inhibitors of P-Glycoprotein
Publication TypeJournal Article
Year of Publication2007
AuthorsKaiser D, Terfloth L, Kopp S, Schulz J, de Laet R, Chiba P, Ecker GF, Gasteiger J
JournalJ. Med. Chem.
Volume50
Issue7
Pagination1698 – 1702
Date Published04/2007
ISSN0022-2623
AbstractSelf-organizing maps were trained to separate high- and low-active propafenone-type inhibitors of P-glycoprotein. The trained maps were subsequently used to identify highly active compounds in a virtual screen of the SPECS compound library.
DOI10.1021/jm060604z
Short TitleJ. Med. Chem.

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